Scorpius Reach

The Scorpius Reach is a large area of space located in the Scorpius-Centaurus Association region of the Beta Quadrant, more than 400 lightyears from Sol.

Despite preliminary observations by long-range probes, the first-manned expedition by the Federation was conducted by the , a vessel chartered by the University of Alpha Centauri in the late 2350s. Shortly afterwards, the, under the command of Captain , was the first Starfleet vessel to enter the region. Captain Donald Varley was also somewhat familiar with the region, and provided maps of the Reach to his friend Jean-Luc Picard. 

Areas surrounding the Reach were home to several cosmozoan species discovered by the USS Intrepid (NCC-1631) in the 23rd century. 

The Scorpius Reach remained largely unexplored into the 2370s. In 2383, the region was one of several considered by Captain Timothy Sinclair as the target of the USS Pendragon's new exploration directive. Ultimately, however, the Pendragon was embarked on a survey of the Great Rift and the galactic rim. (: "Not Home Yet)

By 2385, at least one starship was assigned to an explore the Scorpius Reach. (PDN: "The Light of Distant Shores")