USS Lakota (NCC-42768)

The USS Lakota (NCC-42768) was an Excelsior-class variant Federation starship in service during the 24th century.

Following the Antwerp Conference bombing in 2372, the Lakota transported Captain Benjamin Sisko, Odo and Jake Sisko from Deep Space 9 to Earth.

The Lakota went on to coordinate Starfleet Security forces planetside during Admiral James Leyton's attempted coup d'état, with Leyton declaring martial law. During this time, the Lakota ' s phasers were upgraded and the ship received a supply of quantum torpedoes. 

Under the command of new Captain Erika Benteen, the Lakota intercepted the USS Defiant in an attempt to quell Sisko's anti-coup attempt. The battle between the two ships was muted, as both ships were reluctant to do more than disable the other. As a result, Leyton revised his orders; the Lakota must destroy the Defiant. Benteen refused, standing the Lakota down and allowing Defiant to proceed to Earth. 

In 2376, the Lakota was one of the ships repelling the Vendoth at the Battle of Sol. (: "United We Stand")

Star Trek: Pendragon
In the Pendragon timeline, the Lakota, under Benteen's command, supported Leyton throughout the Federation Civil War.