USS Maryland (NCC-45109)

USS Maryland (NCC-45109) was a cruiser on active duty in Starfleet during the 24th century. (Spacedock!: )

Maryland — along with Proxima and Sarajevo — went missing in the Gamma Quadrant sometime in the 2370s. All three ships were presumed destroyed by the Dominion. 

Background
The vessel was named after the state of, in the on Earth. It may also have been named after previous wet-navy ships and spacecraft named Maryland.