Zhian'tek Syndrome

Zhian'tek Syndrome is a rare condition in which the synaptic connections between host and symbiont become disrupted through the transporter process. About one in 10,000 joined Trills suffer from this condition.

When a joined host-symbiont pair is put through a transporter beam, the condition causes the isoboramine levels in the host become abnormally lowered, which causes an involuntary separation between host and symbiont. This result, unless the effect can be reversed, is inevitably fatal for the host and on occasion, the symbiont as well.

Case Histories
Captain Breawyn Lem of the USS Independence (NX-90201) was known to have this condition and was almost killed as a result of it. ("Starship Independence: War's Embers") She was saved by an experimental genomic regeneration technique developed by the ship's Chief Medical Officer, Dr Orlando Sturges.