|2153 2154 2155 2156 2157 2158 2159|
|2120s 2130s 2140s 2150s 2160s 2170s 2180s|
|21st century - 22nd century - 23rd century|
- Discovery (NX-04) is launched from Earth. (Star Trek: Poseidon - The Birth of the Federation)
- The Mann-class cruiser UESPA Mann (D230) is supposedly lost with her sister ships Zukovski (D237), Dunlap (D241) and the rest of the Fifth Earth Fleet at Gamma Hydra II. In 2295, Team Shadowstar finds the Mann on the third planet of the Ilo Manitou system. (Galactic Engineers Concordance Logbook 6:4 "Starfleet Reference: UESPA Mann "; Star Trek: Shadowstar Station "Through the Looking Glass")
- The UNSS Jutland is missing and is presumed destroyed by Romulan forces. Its flight recorder will be found nearly a century and a half later, 10,000 light years from its last reported position. (Star Trek: Shadowstar Station "Morituri te Salutamus")
- The first of the Earth Outpost Stations is built by the United Earth government, the United Earth Space Probe Agency and the Starfleet Corps of Engineers. (ENT: The Romulan War: To Brave the Storm)
- Ten women are knifed to death in Heliopolis on Alpha Eridani II (aka Achernar II). (TOS: "Wolf in the Fold"; ENT novel: The Romulan War: Beneath the Raptor's Wing)
- Richard Daniels completes a time travel mission to the USS Defiant (NCC-1764) in the mirror universe. While there, Hoshi Sato conceives their son, Jun Sato. (In Between Days: First Born)
- The Earth-Romulan War is precipitated by a Romulan ambush on a United Earth Stellar Navy task force at Station Salem-One. (The Starfleet Museum: Museum Timeline)
- After the attack, United Earth declares war on the Romulan Star Empire. Other members of the Coalition of Planets, especially the Vulcans, are reluctant to join the conflict. (ENT novel: The Romulan War: Beneath the Raptor's Wing)
- 4 May: The United Earth hospital ship Nightingale (MED-6) is destroyed by two Romulan vessels in Sector 2 near the Alpha Centauri system. (The Romulan War: "Nightingale")
- 1 December: Ethan Shapiro and the other Jewish crew members hold a Chanukah party on the Enterprise (In Between Days: The Light).
- 1 November: In the mirror universe, Jun Sato is born to Richard Daniels and Empress Hoshi. In Between Days: Reversal).
- Helena Adiwoso dies and is buried in her family plot on Yogyakarta Baru. (Star Trek: Shadowstar Station)
- 30 November: Rachel Orenstein, great-aunt of Ethan Shapiro, dies on Earth. Her death is considered a major news story as she has lived longer than anyone up to that point. (In Between Days: The Light)