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Samuel Tobias Grissom was a 23rd century Starfleet officer.

In the 2260s, Grissom commanded the Federation-class dreadnought USS Dominion.

Commodore Grissom captained the Dominion during the Cromwell Nebula Incident. The ship received major damage during the incident, resulting in seventeen casualties, including the loss of Commander Don Chamberlain. Grissom was summoned to attended a hearing, following the incident, and was cleared of any wrong doing. The commodore resumed command, nineteen months later, after the vessel's repair.

Grissom eventually accepted a position at Starfleet Academy. At which point, he relinquished command of the Dominion to his former first officer Captain Jason Brousseau. (Dreadnought Dominion)

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