Starbase 22

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Starbase 22 was a United Federation of Planets facility active in the 23rd century.

During the Federation-Klingon War, a cloaked Klingon vessel followed the USS Saratoga into a dock at this facility, and ignited its antimatter supply, resulting in the destruction of most of the ships there. (DIS: "The War Without, The War Within")

It was not specified if this Saratoga was the Constitution-class vessel.

The base was the destination of USS Enterprise after its encounter with a being claiming to be the Mayan god Kukulkan. (TAS: "How Sharper Than A Serpent's Tooth")

In the 2270s, the base was commanded by Commodore David Fein. It was in the general vicinity of "thataway", the heading James T. Kirk ordered after the V'Ger incident. (TOS novel: Ex Machina)

In October, 2288, Starbase 22 dispatched orders to USS Avenger to investigate the disappearance of the skiff Monarch Butterfly in the Menrik star system. Following its recovery, the skiff was towed to the starbase. (Star Trek: Avenger: "Rescue at Menrik")

United Federation of Planets starbases
Starbases: 001 - 1 - 2 - 3 - 4 - 5 - 6 - 7 - 9 - 10 - 11 - 12 - 14 - 15 - 16 - 17 - 18 - 19 - 20 - 21 - 22 - 23 - 24 - 25 - 26 - 27 - 28 - 29 - 30 - 31 - 32 - 33 - 36 - 37 - 38 - 39-Sierra - 40 - 41 - 42 - 43 - 44 - 45 - 47 - 47-Vanguard - 50 - 52 - 53 - 54 - 55 - 58 - 60 - 61 - 62 - 73 - 74 - 77 - 78 - 80 - 86 - 88 - 91 - 105 - 118 - 119 - 125 - 129 - 133 - 134 - 137 - 138 - 140 - 152 - 157 - 176 - 182 - 185 - 188 - 193 - 200 - 201 - 211 - 212 - 214 - 215 - 217 - 220 - 222 - 227 - 234 - 237 - 247 - 310 - 311 - 315 - 332 - 343 - 364 - 371 - 375 - 376 - 395 - 397 - 414 - 505 - 512 - 514 - 515 - 544 - 549 - 592 - 600 - 621 - 718 - 732 - 771 - 804 - 814 - 901 - 911 - Earhart - Earth Spacedock - Echo - Expanse 3 - Expanse 4 - Expanse 7 - Expanse 12 - G-6 - Lya Station Alpha - Narendra Station - Osiris - Pitcairn - Rockford - Strategical Starbase 71 - Unity 1 - Unity 2 - Unity 3
Deep space stations: 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - 9-II -10 - 12 - 14 - 17 - 253 - B-5 - B-5 (Minardverse) - E-5 - K-1 - K-7 - K-12 - K-13
Kelvin timeline: Yorktown
Other Purposes: Fleet Museum