Star Trek Expanded Universe
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The 281st Cruiser Squadron consisted of Constitution-class heavy cruisers that were assembled by Starfleet Command in 2282 and 2283, during a period when the Organians seemed to have lost interest in Federation-Klingon affairs.

The task force was assembled during the Klingon Empire's Taal Tan Offensive. On 12 July 2283, the 281st engaged a squadron of Klingon vessels headed for the Taal Tan system. (The Taal Tan Offensive)

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