Task Force 52 was a Starfleet task force extant in the late 24th century. It was part of the Starfleet Fifth Fleet.
In 2377-78, Rear Admiral Kurt Roithinger was Task Force 52's commanding officer aboard the flagship USS Destiny (an Intrepid-class cruiser commanded by Fleet Captain Stephen Idell). Task Force 52, deployed on patrol missions, was then homeported at Starbase 514. (Ships of the Star Fleet, Vol. 4: Star Fleet Operating Forces. )