The USS Cantabrian (NCC-607) started her Starfleet career as a Pickering-class starship. Around 2271, Starfleet Command issued a directive to refit the Cantabrian to a Constitution class refit.

Captain Thekla Lawless was the commanding officer of the Cantabrian from before 2271 until its destruction during the Tomed Incident in 2311. (Star Trek: The Cantabrian Expeditions: "The Fire In Which We Burn", "In the Still of the Night")

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