USS Constellation (NCC-1974) was the prototype for the Constellation-class cruisers. It was in service in both the 23rd and 24th centuries.
Constellation was commissioned ca. 2275. (TOS novel: Honor Blade)
- According to the Ship Recognition Manual, Volume 4: Starships of the Original Series Era, the Constellation was launched in 2284.
In 2293, the Constellation still held an NX registry number as it completed certification trials. (Star Trek VI: The Undiscovered Country)
Fresh from the Academy, Dr. James Maxwell joined the Constellation medical team as assistant chief medical officer in 2344. Dr. Jason Hargreaves was his superior. (Template:DAE: "First, Do No Harm")
The Constellation arrived at Deep Space 9 in 2371 to ferry a Jem'Hadar child to Starfleet for study. (DS9: "The Abandoned")
In 2374, the ship assisted the USS Defiant, searching for survivors from the USS Honshu, which was attacked by the Cardassians during the Dominion War. (DS9: "Waltz")