The USS Fortune (NCC-78109) was a Miranda-class starship active in the late 24th century, and was part of the Starfleet Third Fleet. (Star Trek: Pioneer)

In 2381, the Fortune rendezvoused with the USS Pioneer after the Pioneer's encounter with Tyson Calok in the Dallos Cluster. ("In Custody")

In 2382, the Fortune was destroyed during the Battle of Minark. ("Torment and Woe")

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