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USS Jamestown (NCC-1843-C) was an Ambassador-class heavy cruiser on active duty in Starfleet from 2330 to 2362. It was the eighth spacecraft to bear the name. (Starfleet International: USS Jamestown)

Some of Jamestown-C's most important missions were under the command of Captain Jack Armstrong.

Jamestown-C was reported lost in 2362.

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