The USS Lalo (NCC-43837) was a Mediterranean-class frigate that saw service with the Federation Starfleet during the 24th century. (Star Trek Encyclopedia; Ship Recognition Manual, Volume 1: The Ships of Starfleet)

In 2364, the Lalo reported temporal distortions caused by Dr. Paul Manheim. (TNG: "We'll Always Have Paris")

Two years later the Lalo was destroyed by the Borg bear Zeta Alpha II. (TNG: "Best of Both Worlds")

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