Star Trek Expanded Universe
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The USS Persephone was an Excelsior-class starship in service in 2410, operating as a training vessel for Starfleet Academy. Captain Radescu was her commanding officer. (Chronicle: "Best Laid Plans")

During the Dominion War in late 2374, the Persephone was a part of Starfleet Second Fleet which participated in Battle of Betazed. (Chronicle: "Best Laid Plans") Captain Skovaan was her commanding officer during the Dominion War. (Chronicle Series Bible)

In 2410, the Persephone was surveying an Oort cloud in the Deneva system. The Puerto Rico-class runabout USS Malta rendezvoused with the Persephone en route to the runabout's new posting, the USS Witch of Endor, to upload Ensigns Athena Azurian and V'Nell.

Upon seeing the Persephone, Ensign Nath Behal called her "a piece of junk", but Lieutenant junior grade Zachary Stiles countered the ship was "a classic". (Chronicle: "Best Laid Plans")

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